It depends on what that 2" pipe is doing on the Run of the wye. Is that going up to a bathroom sink, tub/shower that is vented using proper horizontal venting? Then yes, it would be vented.
It looks like that stack connection is a double wye for use in back to back toilet scenarios. which typically dont work for venting, but since toilets don't rely on venting as a means of trap seal maintenance it does work as venting and cross flow.