PEX (water) supply lines can't be within the last 18" of the WH connection (and should stay clear of the vent/chimney)...you must either use metal flex lines, or hard pipe it with copper. The only other gotcha you might have is if you cannot maintain the proper slope of the gas vent line...it depends on how tall it is, and where the vent line currently runs relative to the top of the WH. In a garage, you need to protect the thing from being potentially hit, and if it isn't a newer version with the FLIR (?) mods, it needs to be up off of the garage floor. If you're required, you might need earthquake straps, even if it is only temporary. There might be more that I'm not aware of.