So maybe it is related. I would expect a clog to happen at about place B, where the long sweep should be.
However E should have been a combo( combination wye and 45). So maybe that would lead to a clog around there.
You do have a cleanout in that horizontal. Maybe you could rod to the right of that, but there are two elbows that might be hard to get through. It would be nice if you could rod from D and through C and on up. If you fix all of this, consider a bidirectional cleanout at D.
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It's possible that your earlier rodding efforts from the bathroom ran the snake up into the vent system rather than down to C-D-E and beyond.
I could try and snake from the clean out, but I’ve had zero problems (so far) with the kitchen sink that drains out this white PVC - I’ve never tried it yet though. Is it still advisable? Also, is there any method on getting the snake up to D rather than heading down? Much appreciated!!!!