I assume (dangerous, I know) that you're changing things from 120vac to 240vac? If so, and you run a 240vac circuit, if you combine the black and red, then turn on the circuit breaker, it will, or should immediately trip - it might be quite dramatic!
Neutral is a current carrying conductor. You don't want ground carrying current. It's only there for a fault. So, assuming it is a 240vac circuit, and you're running a cable with red/black/white/ground, you do NOT need the white lead at all and it should be capped off at both ends UNLESS, there's something in the tub that needs 120vac, then, you'd need to find where the neutral would be, and then, you'd have 120vac available as well. You'd connect red to one side of the heating element, and black to the other, and current would run from one to the other, just like it would or did when you had the black on one and white on the other. Ground should go to the ground point. Note, if ground and neutral are currently connected to the same point, and, the neutral is now connected to one side of the heating element, you MUST isolate neutral from the heating element if you're going to feed it with 240vac.
This does not mean that your cabling or circuit breaker are properly sized for this application. 5500W at 240vac 5500/240=22.9A. and for the required margin, you'd need a 30A circuit to power it (code wants no more than 80% of the max on a circuit like this that could be on for a long time).
The safer thing to do if you're not comfortable with this, is to hire someone, or find someone who actually knows what they are doing...electricity can kill you. If this isn't protected via a GFCI, you should consider incorporating one into it. Be safe.