Each layout is slightly different due to where the tile and grout lines will fall. I had 4 tiles coming together and was able to cut a hexagon around the opening for the pipe. I just stuck the verticies close to where a screw would go into the floor through to the subfloor. Where a screw didn't meet a verticie, I just notched the tile with my tile cutter for the screw. My floor is 1" plank deck, 3/4" CDX plywood, 1/4" tile backer, & 1/4" floor tile. I used 2-1/2", #12 stainless steel screws. I also applied a light bead of silicone sealer around the tile opening, closest to the pipe to keep any water finding its way underneath the flange from dripping down on the ceiling below. Don't put any silicone on the outside of the flange because you want water getting in there to run out into the room.