Charlie gets a colonoscopy on Two and a Half men tonight on CBS at 9:00PM It's something that all men should get at fifty. Is Charlie already 50? Which of the men here over fifty have had theirs? A Preview of tonights episode. In case you're wondering why I'm posting this, I waited until I was 57 before I did one. I chose the Chemo, Radiation and major surgery option. Surgery will be on the 4th.